Alendronate: Fosamax

Key Patient Counseling Points:

  • Swallow the non-effervescent tablet whole with a large glass (8 oz) of plain water only.
  • Dissolve one effervescent tablet in 4 oz of room temperature plain water only (not mineral water or flavored water); once effervescence stops, wait ≥5 min and stir the solution for about 10 seconds and then drink.
  • Wait at least 30 min after you swallow the tablet before you eat or drink anything or take any other medicines. This will help your body absorb the medicine.
  • Do not lie down for at least 30 min after taking this medicine, and do not lie down until after you have eaten some food.



Mechanism of Action:

Alendronate binds to bone hydroxyapatite, and at the cellular level, inhibits osteoclast activity, thereby modulating bone metabolism.


Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s