Key Patient Counseling Points:
- If using chronically, use a stool softener and/or laxative for preventing constipation.
- May cause drowsiness; avoid driving or other tasks requiring motor coordination.
- Avoid alcohol.
Opioid/Acetaminophen Combination Product. C-III
Mechanism of Action:
Acetaminophen is a central inhibitor of prostaglandin synthesis. It has no effects on platelets. Codeine is 3-methoxymorphine, a phenanthrene opioid with very low affinity for opioid receptors. Its analgesic activity appears to result from conversion to morphine.